With the last-16 first leg delicately poised and goalless as the hour mark approached, the Argentine introduced forwards Angel Correa, Alvaro Morata and Thomas Lemar, and the Spanish side went on to win 2-0.
Atletico Madrid boss Diego Simeone has also caused a stir. "Doing what we have done over these years is not easy, and today we did it again".
"I felt that playing Costa and Koke after a month and a half had to take b***s", he said of his celebration afterwards.
The reaction elicited divided opinion among fans on social media, with some openly expressing their administration for the celebration.
Ronaldo helped to down Atletico in the 2014 and 2016 finals, which were each level after 90 minutes, Los Blancos going on to win those titles in extra time and on penalties respectively. "I will tell you in the next interview".
Then as he left the stadium he reiterated the point while making a gesture of one hand open -5- before making zero: "I have won five Champions League and Atletico have none". This is what we are and we aren't going to change.
Juventus manager Massimiliano Allegri criticised his side for switching off in the closing stages and for not showing patience.
Atletico will be without Thomas Partey and Diego Costa for the match, who are suspended due to an accumulation of yellow cards, yet if they are able to score one solitary goal, Juventus would need to score four; an nearly impossible task against the best goalkeeper in the world in Oblak. "We fully expect to suffer in the second leg".
"And they came through, both of them".
"We had put in a great performance against Borussia Dortmund", added Simeone. We'll need a flawless game to get through.
Juventus will bid to overturn a two-goal deficit in the return leg in Turin on March 12. "But we have to believe until the end".