It was a stunning result after so much hype surrounding the contest going into Sunday night with Velasquez returning for the first time in more than two years and Ngannou looking for a statement win to prove he's ready for title contention once again.
Ngannou bouncing back in his last bout seemed to stave off numerous criticisms he had after two losses in a row but facing Velasquez as the ultimate proving ground to see if he was ready to contend for a title again one day soon.
Ngannou landed two heavy strikes with his hands but it was mainly a consistent flurry of glancing strikes that did the damage as Velasquez fell backwards with his left knee buckling under him and rendering him incapable of defending himself from the ground. "I hope you liked it".
Ngannou answered those questions emphatically after a rapid fire exchange with Velasquez that brought a swift end to the former champion's night.
As for Ngannou, he earned his second first round knockout in a row after finishing Curtis Blaydes last November and now he's added a two-time former heavyweight champion to his resume as well.
It was a total bummer for those watching on ESPN - not because Ngannou won, he's the type of fighter that makes you stop and watch his fights when they're on and it's good to see that he's back to being a factor in the heavyweight division.
"I won't go fight Francis Ngannou", Cormier emphasized. Completely different fighter than I was before.
"He was really fast, so I didn't even realize what happened", Ngannou said, via UFC.com. I'm honored to be here.
"Just very disappointed, I know how hard he trained", DC said.
Preliminary fight action will be shown from midnight before the main event coverage gets underway at 2am. "What are you going to do?"
Velasquez said in his postfight interview with ESPN's Jon Ank that he felt super ready for the fight and he's not sure when he'll be back next. This is why this sport is so great. "I'm truly sorry for this".