First baby born via uterus transplanted from dead donor

Image    The transplant surgery lasted 10.5 hours. File pic

Image The transplant surgery lasted 10.5 hours. File pic

A healthy baby girl has been born using a uterus transplanted from a dead donor, doctors say.

The patient was a 32-year-old woman with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a rare genetic disorder that causes the vagina or uterus to either under-develop or not develop at all.

He said any doubts he had about the potential importance of uterus transplants were erased after meeting the mother of the first baby born after a live donor uterus transplant.

The 10.5-hour transplant surgery took place in September of 2016.

The baby girl was delivered via C-section last December weighing 6lbs.

The use of a deceased donor is a significant achievement that could greatly increase access to the procedure, said Stefan Tullius, chief of transplant surgery at Brigham and Women's Hospital in Boston who has participated in living donor uterus transplant surgery.

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it.

In total, there have been 39 procedures of this kind, resulting in 11 live births so far.

Previously, there have been 10 other uterus transplants from deceased donors attempted in the US, Czech Republic and Turkey, but this is the first to result in a live birth.

"They should promote education and guidance so that the groups performing uterus transplantation for the first time can benefit from the experience of the pioneers".

It said the case involved connecting veins from the donor's uterus with the recipient's veins, as well as linking arteries, ligaments, and vaginal canals.

"She couldn't keep the uterus in another pregnancy", said Dr. Wellington Andraus, who worked on her transplant team.

Aside from relying on a deceased donor for their uterine transplant, the doctors might have also made the procedure less costly and unsafe.

She received five immunosuppression drugs, as well as antimicrobials, anti-blood clotting treatment and aspirin while in hospital.

The breakthrough opens up the possibility of harvesting wombs from donor patients after death in the same way as other organs, ending the need for live donors.

She stayed in intensive care for two days after the surgery and then spent six more on a specialised transplant ward.

Five months before the transplant, the recipient had sixteen eggs from her own functional ovaries removed. Babies have been born after womb transplants from live donors, typically from a relative, but using organs from dead donors could widen the...

According to data included in the new report, among infertile couples, one in 500 have uterine infertility due to factors such as birth defects, hysterectomy or infection.

More: Hospitals know how to protect mothers. Fifteen were fertilised, with 8 resulting in embryos that were subsequently preserved for later implantation.

Experts hope uterus transplants will one day be more widely available for women without uteruses or with damaged organs - or potentially even transgender women - seeking to become pregnant.

Later the doctors fertilised her eggs with the father-to-be's sperm and freezed them.

At the age of seven months, the baby continued to breastfeed and weighed 15lbs and 14oz (7.2 kilos).

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