The All-India Senior Selection Committee, meanwhile, has added Siddarth Kaul to the squad.
"The Indian team management has chose to rest Umesh Yadav, Jasprit Bumrah and Kuldeep Yadav from the upcoming third Paytm T20I against the Windies in Chennai", BCCI acting secretary Amitabh Choudhary said in a release.
Kaul, who made his T20I debut against Ireland in Dublin in June earlier this year, has so far featured in two matches. As a result, in walks seam bowler Siddarth Kaul into the squad.
Rohit Sharma's unbeaten 111 off 61 balls powered India to a commanding 195 for two wickets, and he returned to marshal his bowlers who restricted Windies to 124-9 to earn an unassailable 2-0 lead in the three-match series.
In the two games, left-arm spinner Kuldeep picked up five wickets, including 3 for 13 at Kolkata while Bumrah took three wickets.
Jasprit Bumrah has been India's X-factor in the bowling attack and is now an integral member of the team in all the three formats.
The decision was taken keeping in mind the T20I series against Australia commencing on 21 November so that the players can get enough rest.
India's squad for third T20IRohit Sharma (capt), Shikhar Dhawan, KL Rahul, Dinesh Karthik (wk), Manish Pandey, Shreyas Iyer, Rishabh Pant (wk), Krunal Pandya, Washington Sundar, Yuzvendra Chahal, Bhuvneshwar Kumar, Khaleel Ahmed, Shahbaz Nadeem, Siddarth Kaul.