Sayoc faces almost 50 years in prison if convicted on five federal charges that were filed in NY because some of the devices were recovered there.
"Our political leaders, like our President Donald Trump, need to recognize that there are many sick people in this country who take their rhetoric and words of "War with the Media" and "War with the Democrats" to heart", Madeline Sayoc wrote.
Prosecutors have said Sayoc is likely to face additional charges and penalties as their investigation proceeds, and should be detained pending trial because he is unsafe and a flight risk.
Sayoc, 56, appeared before a Manhattan federal court for just a few minutes.
Sayoc last week waived a similar hearing in Miami near where he was captured on October 26. Sayoc was charged with the mailing of explosives, threatening a former president, making threatening interstate communications and assaulting federal officers, according to The Independent.
He was living in a van covered plastered with stickers of Mr Trump and images of some of the United States president's opponents with red crosshairs over their faces.
His lawyer has questioned the evidence in the case.
None of the devices exploded before being intercepted and no one was hurt.
Sayoc is accused of sending 15 devices fashioned like pipe bombs to targets including former President Barack Obama, former Secretary of State Hillary Clinton, former Vice President Joe Biden, former Central Intelligence Agency director John Brennan, billionaire investor-philanthropist Georg Soros, actor Robert De Niro, CNN and others.
Sayoc is scheduled to return to federal court Monday for a preliminary hearing. Kamala Harris and New Jersey Sen.
Prosecutors say the most recent crude bomb was recovered Friday in California, addressed to the liberal activist Tom Steyer.
"My son has been ill for a long time and my family and I have tried, over and over again, without success to urge him to get the help he needs", she wrote.