Bradford completed 27-of-32 passes for 346 yards with three touchdowns and zero interceptions in a 29-19 season-opening win over New Orleans on Monday.
Smith was named AFC Offensive Player of the Week.
Just a couple days removed from putting up the best performance of his career, Bradford was limited in practice Wednesday with what is being reported to be a knee injury.
Teams aren't required to be all to specific with regards to listed injuries, so it's unknown which knee was giving Bradford trouble.
Practicing fully for the Vikings on Wednesday were guard Danny Isidora (knee) and cornerback Tramaine Brock (groin). And being a limited participant at this point in the game week really doesn't reveal too much with regards to his status for Sunday's game. Bradford's 2013 season ended after seven games due to a torn ACL, and another ACL injury in the 2014 preseason sidelined him for the entire season. Bradford, who went 27 of 32 passing for 346 yards and three touchdowns with a 143.0 passer rating, convinced National Football League honchos that he was the NFC Offensive Player of the Week.